FA16 Immunization Module’s Updates

Immunizations in the geriatric community: Why older adults need vaccines too

Recommended immunization schedule for adults aged 19 years or older, by vaccine and age group* - United States, 2016

When we talk about vaccination, we frequently refer to the need for vaccinating children. However, noting the increased susceptibility of infections in older adults, vaccinations can be critical in preventing serious health implications in the elderly. With several classes of vaccines requiring boosters at various schedules, it becomes difficult for both patients and providers to keep up with the recommended immunizations. For instance, USPSTF recommends that adults receive a tetanus-diphtheria toxoid (DTaP) booster every ten years, with older adults over 60 years old accounting for around 60 percent of tetanus cases in the United States [1]. Although clinical tetanus is relatively rare in the U.S., rates are on the rise due to a number of reasons, with a decline in childhood vaccinations being one particular factor [2]. 

One of the most severe infections that older adults can contract is seasonal influenza, with more than 90 percent of deaths occurring in individuals over 60 years old. A serious complication arising from influenza-related infection is acute-respiratory failure, which affects older adults 10-30 times more than younger adults. The inactivated influenza vaccine (IIV) is the only vaccine class approved for administration in adults over 65 [1]. Although the effectiveness of these vaccines is not thoroughly understood, it has been previously shown to produce a 43 percent effectiveness rate against influenza-like illness. Nevertheless, an effectiveness of merely 40 percent has been estimated to avert nearly 60,000 hospitalizations of older adults for complications due to pneumonia and influenza. Factors such as impaired herd immunity in older, immunosuppressed adults in addition to suboptimal immunization results has led to outbreaks in nursing homes even though 80-98 percent of the residents were vaccinated. Additional factors such as statin administration (which are implicated in influencing the immune system) by hyperlipidemic patients could potentially subvert the immunization effects of the vaccine [3]. 

As a whole, the main issue with understanding the necessary protocols for vaccinating adults is the lack of information/research available on the subject. Considering the vulnerability of the immune system at both extremes in age deserves special attention. When it comes to setting up a discrete schedule/timing of vaccines in older adults, the specifics are ambiguous. Better measures and more concrete guidelines should be made to direct providers in a more efficient manner when taking care of the geriatric population.

 

 

 

1.    J Am Geriatr Soc. 2015;63(3):584-588. http://www.medscape.com/viewarticle/842397_1.
2.    https://www.uptodate.com/contents/geriatric-health-maintenance?source=search_result&search=vaccines%20geriatric&selectedTitle=1~150#H9
3.    https://www.uptodate.com/contents/seasonal-influenza-vaccination-in-adults?source=see_link&sectionName=Older%20adults&anchor=H14#H14

  • Erika Becerra
  • Richard Tapping
  • Victoria Lu
  • Gabriel Swords